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DeCS

Descriptor English:

CLOCK Proteins

Descriptor Spanish:

proteínas CLOCK

Descriptor Portuguese:

Proteínas CLOCK

Synonyms English:

CLOCK Protein
Circadian Locomotor Output Cycles Kaput Proteins

Tree Number:

Definition English:

Basic helix-loop-helix (bHLH) domain-containing proteins that contain intrinsic HISTONE ACETYLTRANSFERASE activity and play important roles in CIRCADIAN RHYTHM regulation. Clock proteins combine with Arntl proteins to form heterodimeric transcription factors that are specific for E-BOX ELEMENTS and stimulate the transcription of several E-box genes that are involved in cyclical regulation. This transcriptional activation also sets into motion a time-dependent feedback loop which in turn down-regulates the expression of clock proteins.

History Note English:

2010(1997)

Allowable Qualifiers English:

Record Number:

53609

Unique Identifier:

D056926

Similar:

DeCS